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I. Development of therapeutical agents and proteins

Therapeutic agents and proteins can be produced in large amounts and with great purity by using bioreactors and biotechnologically optimized recombinant expression systems. Projects in category I will use the expertise available in the research focus area of protein biochemistry. New therapeutic agents with effects on known pathologically relevant proteins as well as new proteins with relevance for known pathologies will be identified and characterized. Biochemical research on such agents and proteins requires substantial experise and equipment, which are both available on-site in Halle.

Project 1-1

Prof. Dr. Frank Bordusa (MLU Biochemistry and Biotechnology)

• Immobilization of trypsiligase for the production of antibody derivatives for industrial applications

Project 1-2

Prof. Dr. Stefan Hüttelmaier (MLU Medicine)

• Novel chemotherapeutica: IGF2BP-directed agents in cancer therapy

Project 1-3

PD Dr. Lutz Müller (MLU Medicine)

• Therapy of malignant diseases with multipotent stem cells

Project 1-4

Prof. Dr. Markus Pietzsch (MLU Pharmacy)

• Development of a production strain and a fermentation process to produce trypsiligase

Project 1-5

Prof. Dr. Wolfgang Sippl (MLU Pharmacy)

• Development of novel epigenetic inhibitors as anti-parasitic agents

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