Martin Luther University Halle-Wittenberg

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LSP Project 2-5

The Trojan horse strategy: An innovative method to control human- and phytopathogenic fungi

It is widely accepted that fungal pathogens have an enormous potential to affect plant, animal and human health. During the life time every fourth human (or ~ 1.7 billion) suffers from least one fungal infection. Of particular concern is the high rate of mortality (up to 95%) associated with invasive fungal mycosis, which often cannot be treated with several available antifungal drugs. Those antifungal drugs are not only used in human healthcare but also in agriculture. But during the last decade a decrease of efficiency of diverse antifungal compounds was observed. Further complications include the toxicity, undesirable drug interactions, and bioavailability in target tissue, thus limiting the development and release of new therapeutic agents (Brown et al., 2012). Therefore the development of an innovative strategy is essential to fight against such pathogenic fungi.

Staff

Prof. Dr. Holger Deising

Prof. Dr. Holger Deising

Prof. Dr. Holger Deising

Prof. Dr. Holger Deising, Projektleiter

Tel: 0345 55 22660

Prof. Dr. René Csuk

Prof. Dr. René Csuk

Prof. Dr. René Csuk

Prof. Dr. René Csuk, Projektleiter

Tel: 0345 55 22660

Dr. Anja Raschke, Projektleiter

Tel: 0345 55 22664

Jessica Heilmann

Jessica Heilmann

Jessica Heilmann

Jessica Heilmann

Tel: 0345 55 22671

Immo Serbian

Immo Serbian

Immo Serbian

Immo Serbian

Tel: 0345 55 25790

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